IN SILICO MINING AND VALIDATION OF SIMPLE SEQUENCE REPEAT (SSR) MARKERS DERIVED FROM THE FRAGARIA X ANANASSA GENOME ASSEMBLY

IN SILICO MINING AND VALIDATION OF SIMPLE SEQUENCE REPEAT (SSR) MARKERS DERIVED FROM THE FRAGARIA X ANANASSA GENOME ASSEMBLY

V.H. ELEC, C.A.E. CADORNA, and J.D. REY

Citation: Elec VH, Cadorna CAE, Rey JD (2023). In silico mining and validation of simple sequence repeat (SSR) markers derived from the Fragaria x ananassa genome assembly. SABRAO J. Breed. Genet. 55(5): 1573-1586. http://doi.org/10.54910/sabrao2023.55.5.11.

Summary

Strawberry (Fragaria x ananassa Duchesne ex Rozier) is an economically important fruit crop grown commercially worldwide due to its known nutritional value. The demand for strawberries in the Philippines has been increasing but varietal development is slow due to the lack of genetic information on locally available germplasm. In addition, molecular marker resources for strawberries are limited. Here, we developed Simple Sequence Repeats (SSR) markers to characterize strawberries cultivated in tropical environments, particularly in the Philippines. In silico mining generated a total of 219,239 SSR markers, from which 160,025 unique markers were identified. Polymorphism scoring and the variation on the expected alleles resulting to the synthesis of the top 160 markers were validated using representative strawberry cultivars from the core collection. All 70 markers produced successful amplicons from all the genotypes, but only 67 markers displayed polymorphism. Using UPGMA, genetic similarities among the cultivars were calculated generating a dendrogram which categorized the strawberry cultivars into 3 groups. The grouping clearly showed the separation of the diploid Fragaria vesca from the octoploid F. x ananassa cultivars, considered as group 1. Furthermore, Groups 2 and 3 contained cultivars from different geographical origins (US, Japan, and North America). The eight novel markers developed and validated here can be added to the genetic marker resource for cultivar verification, assessment of genetic diversity, and most importantly, marker-assisted breeding.

In silico mining, Fragaria genome, Philippine strawberry cultivars, simple sequence repeats

In silico mining from F. x ananassa genome sequence generated a total of 160,025 unique markers from which a subset of 70 markers was validated and approximately 95.7% (67 markers) are polymorphic. These markers were able to discriminate representative strawberry cultivars from the core collection of the BSU breeding program. It can also be utilized to further characterize and fingerprint these sets of germplasm as a prerequisite for a successful breeding programs.

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SABRAO Journal of Breeding and Genetics
55 (5) 1573-1586, 2023
http://doi.org/10.54910/sabrao2023.55.5.11
http://sabraojournal.org/
pISSN 1029-7073; eISSN 2224-8978

Date published: October 2023

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